Basic information of VEGFA :
| Official Symbol of Gene | VEGFA |
| Species | Homo sapiens |
| Entrez Gene ID | 7422 |
| Official Full Name | vascular endothelial growth factor A |
| Also known as | VPF; VEGF; MVCD1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112715 MIM:192240; AllianceGenome:HGNC:12680 |
| Map Location | 6p21.1 |
| Variation Type | genotype |
| refSNP ID | rs1413711(C/C) |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | MS (n = 28) and without MS (n = 47) |
Literature information of multiple sclerosis :
| Pubmed ID | 33121296 |
| Year | 2021 |
| Title | Association of VEGFA, TIMP-3, and IL-6 gene polymorphisms with predisposition to optic neuritis and optic neuritis with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The distribution of VEGFA rs1413711 genotypes (T/T, T/C, C/C) was statistically significantly different in the ON without MS group compared to the control. |
| Mechanism/Pathway | A VEGFA role in MS development and overall in CNS inflammation when contributing together with adhesive molecules. |
