Basic information of TIMP3 :
| Official Symbol of Gene | TIMP3 |
| Species | Homo sapiens |
| Entrez Gene ID | 7078 |
| Official Full Name | TIMP metallopeptidase inhibitor 3 |
| Also known as | SFD; K222; K222TA2; HSMRK222 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000100234 MIM:188826; AllianceGenome:HGNC:11822 |
| Map Location | 22q12.3 |
| Variation Type | genotype |
| refSNP ID | rs9621532(C/C) |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | MS (n = 28) and without MS (n = 47) |
Literature information of multiple sclerosis :
| Pubmed ID | 33121296 |
| Year | 2021 |
| Title | Association of VEGFA, TIMP-3, and IL-6 gene polymorphisms with predisposition to optic neuritis and optic neuritis with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our results showed that the IL-6 rs1800796, TIMP-3 rs9621532, and IL-6 rs1800796 were not associated with ON with MS development. |
| Mechanism/Pathway | However, there are good insights into the role of proteases in neuroinflammation. |
