Basic information of IL6 :
| Official Symbol of Gene | IL6 |
| Species | Homo sapiens |
| Entrez Gene ID | 3569 |
| Official Full Name | interleukin 6 |
| Also known as | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018 |
| Map Location | 7p15.3 |
| Variation Type | genotype |
| refSNP ID | rs1800796(C/C) |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | MS (n = 28) and without MS (n = 47) |
Literature information of multiple sclerosis :
| Pubmed ID | 33121296 |
| Year | 2021 |
| Title | Association of VEGFA, TIMP-3, and IL-6 gene polymorphisms with predisposition to optic neuritis and optic neuritis with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Our results showed that the IL-6 rs1800796, TIMP-3 rs9621532, and IL-6 rs1800796 were not associated with ON with MS development. |
| Mechanism/Pathway | IL-6 tends to shift the RGCs towards regenerative phenotype after damage to the optic nerve. |
