Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DRB1*1501 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Sweden |
| Sample Size | 40 Swedish patients with MS, 21 Swedish patients with ON, 101 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1349586 |
| Year | 1992 |
| Title | Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The present study shows that, in Scandinavians, MS is associated with DRB1*1501, DQAI*0201, and DQBl*0602. |
| Mechanism/Pathway | N/A |
