Basic information of HLA-DPA1 :
| Official Symbol of Gene | HLA-DPA1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3113 |
| Official Full Name | major histocompatibility complex, class II, DP alpha 1 |
| Also known as | DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000231389 MIM:142880; AllianceGenome:HGNC:4938 |
| Map Location | 6p21.32 |
| Variation Type | polymorphisms |
| refSNP ID | DPA1*0103 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Sweden |
| Sample Size | 40 Swedish patients with MS, 21 Swedish patients with ON, 101 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 1349586 |
| Year | 1992 |
| Title | Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | The frequencies in MS of DPw4- associated DNA fragments were not significantly increased although the RR of DPAI*0103 was 2.9 (not significant) and DPB1*04 was 2.5 (not significant). |
| Mechanism/Pathway | N/A |
