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Basic information of HLA-DPB1 :

Official Symbol of Gene HLA-DPB1
Species Homo sapiens
Entrez Gene ID 3115
Official Full Name major histocompatibility complex, class II, DP beta 1
Also known as DPB1; HLA-DP; HLA-DPB; HLA-DP1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940
Map Location 6p21.32
Variation Type polymorphisms
refSNP ID DPB1*04

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype RRMS
Population Sweden
Sample Size 40 Swedish patients with MS, 21 Swedish patients with ON, 101 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 1349586
Year 1992
Title Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result The frequencies in MS of DPw4- associated DNA fragments were not significantly increased although the RR of DPAI*0103 was 2.9 (not significant) and DPB1*04 was 2.5 (not significant).
Mechanism/Pathway N/A