Basic information of NFASC :
| Official Symbol of Gene | NFASC |
| Species | Homo sapiens |
| Entrez Gene ID | 23114 |
| Official Full Name | neurofascin |
| Also known as | NF; NRCAML; NEDCPMD |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000163531 MIM:609145; AllianceGenome:HGNC:29866 |
| Map Location | 1q32.1 |
| Variation Type | SNP |
| refSNP ID | rs12368653 |
Sample information of multiple sclerosis:
| Detected Sample | grey matter tissue |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | SPMS |
| Population | N/A |
| Sample Size | 23 MS cases and 12 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 26785938 |
| Year | 2017 |
| Title | Axonal motor protein KIF5A and associated cargo deficits in multiple sclerosis lesional and normal-appearing white matter |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The results showed a significant increase in dephosphorylated NF expression in patients heterozygous (AG/AG; p<0.05) or homozygous (AA/AA; p<0.05) for both the rs12368653 and rs703842 risk SNP, when compared to patients with no copy of either SNP. |
| Mechanism/Pathway | N/A |
