Basic information of TRIM5 :
| Official Symbol of Gene | TRIM5 |
| Species | Homo sapiens |
| Entrez Gene ID | 85363 |
| Official Full Name | tripartite motif containing 5 |
| Also known as | RNF88; TRIM5alpha |
| Gene Type | N/A |
| dbXrefs | Ensembl:ENSG00000132256 MIM:608487; AllianceGenome:HGNC:16276 |
| Map Location | 11p15.4 |
| Variation Type | SNP |
| refSNP ID | rs3802981 |
Sample information of multiple sclerosis:
| Detected Sample | blood sample |
| Sample Detail | blood sample |
| Detected Method | a SequenomH platform (San Diego, California) and the iPLEX gold reaction |
| Disease | MS |
| Disease subtype | N/A |
| Population | Danish patients |
| Sample Size | patients and controls in 4 cohorts |
Literature information of multiple sclerosis :
| Pubmed ID | 21311761 |
| Year | 2011 |
| Title | The etiology of multiple sclerosis: genetic evidence for the involvement of the human endogenous retrovirus HERV-Fc1 |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | We conclude that HERV-Fc1 and TRIM5 play a role in the etiology of multiple sclerosis. |
| Mechanism/Pathway | N/A |
