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Basic information of TRB :

Official Symbol of Gene TRB
Species Homo sapiens
Entrez Gene ID 6957
Official Full Name T cell receptor beta locus
Also known as TCRB; TRB@
Gene Type protein coding
dbXrefs AllianceGenome:HGNC:12155
Map Location 7q34
Variation Type allele
refSNP ID Cβ

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population French
Sample Size 48 pairs of monozygotic and dizygolic twins, 63 unrelated MS patients

Literature information of multiple sclerosis :

Pubmed ID 8105988
Year 1993
Title Multiple sclerosis susceptibility: population and twin study of polymorphisms in the T-cell receptor beta and gamma genes region.French Group on Multiple Sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result However one Vβl I , 25 kb allele and a haplotype defined by Vβl I and Cβ alleles showed a correlation with MS susceptibility of borderline significance.
Mechanism/Pathway N/A