Basic information of HLA-B :

Official Symbol of Gene	HLA-B
Species	Homo sapiens
Entrez Gene ID	3106
Official Full Name	major histocompatibility complex, class I, B
Also known as	AS; HLAB; B-4901
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932
Map Location	6p21.33
Variation Type	allele
refSNP ID	HLA-B7

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	Lymphocytes
Detected Method	N/A
Disease	MS
Disease subtype	N/A
Population	Caucasians
Sample Size	56 Caucasian MS patients and 72 healthy control Caucasians

Literature information of multiple sclerosis :

Pubmed ID	1085490
Year	1976
Title	Multiple sclerosis and high incidence of a B lymphocyte antigen

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	Therefore, the HLA-D locus is probably closely related to the locus that deter- mines the group 4 antigen. In contrast,HLA-B7 is almost completely included in the group 4 antigen among MS patients, but not among the normal population.
Mechanism/Pathway	The antiserums defining the five other B lymphocyte specificities reacted at a lower frequency to B cells from multiple sclerosis patients, showing that increased reactivity to group 4 antiserums was specific.