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Basic information of IL25 :

Official Symbol of Gene IL25
Species Homo sapiens
Entrez Gene ID 64806
Official Full Name interleukin 25
Also known as IL17E
Gene Type protein coding
dbXrefs Ensembl:ENSG00000166090 MIM:605658; AllianceGenome:HGNC:13765
Map Location 14q11.2
Variation Type polymorphisms
refSNP ID IL-25 exon1

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail serum
Detected Method PCR
Disease MS
Disease subtype RRMS
Population Iranian
Sample Size 100 Relapsing-Remitting MS cases, and 100 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 25143869
Year 2014
Title Molecular analysis of interleukin-25 exons 1 and 2 and its serum levels in Iranian patients with multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result However, no significant differences were found in polymorphisms for IL-25 exon.
Mechanism/Pathway Considering the role of IL-25 in suppression of the effects of IL-17A and active phase of Experimental Autoimmune Encephalomyelitis (EAE) in vivo