Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | SNP |
| refSNP ID | HLA-DRB1*15 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | SSP-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iranian |
| Sample Size | 336 MS patients/454 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 29067976 |
| Year | 2017 |
| Title | Combination of interleukin-10 gene promoter polymorphisms with HLA-DRB1*15 allele is associated with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | DRB1*15 allele showed a higher frequency among MS patients as compared with control subjects. |
| Mechanism/Pathway | N/A |
