Basic information of FAS :
| Official Symbol of Gene | FAS |
| Species | Homo sapiens |
| Entrez Gene ID | 355 |
| Official Full Name | Fas cell surface death receptor |
| Also known as | APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000026103 MIM:134637; AllianceGenome:HGNC:11920 |
| Map Location | 10q23.31 |
| Variation Type | SNP |
| refSNP ID | a band at 189 bp (allele G) or a band at 233 bp (allele A) |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMS,SPMS |
| Population | Japanese |
| Sample Size | 114 patients/121 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 12188927 |
| Year | 2002 |
| Title | An examination of the Apo-1/Fas promoter Mva I polymorphism in Japanese patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | We found no evidence that the polymorphism contributes to susceptibility to MS. Furthermore, there was no association between Apo-1/Fas gene polymorphisms and clinical course .No significant association was observed between Apo-1/Fas gene polymorphisms and the age at disease onset. |
| Mechanism/Pathway | N/A |
