Basic information of HLA-A :
| Official Symbol of Gene | HLA-A |
| Species | Homo sapiens |
| Entrez Gene ID | 3105 |
| Official Full Name | major histocompatibility complex, class I, A |
| Also known as | HLAA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000206503 MIM:142800; AllianceGenome:HGNC:4931 |
| Map Location | 6p22.1 |
| Variation Type | SNP |
| refSNP ID | HLA-A*02+/- |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | RR-MS,P-MS |
| Population | N/A |
| Sample Size | 62 MS patients/64 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 29587799 |
| Year | 2018 |
| Title | HLA alleles modulate EBV viral load in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result |
The relationship between HLA alleles and viral parameters was exclusively seen in MS patient.A significantly lower EBV viral load was observed in MS patients expressing the HLA-A*02 antigen (HLA-A*02+) , which is suggested to be a protective factor in MS, compared to those without the allele (HLA-A*02 |
| Mechanism/Pathway | N/A |
