Basic information of HLA-B :
| Official Symbol of Gene | HLA-B |
| Species | Homo sapiens |
| Entrez Gene ID | 3106 |
| Official Full Name | major histocompatibility complex, class I, B |
| Also known as | AS; HLAB; B-4901 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932 |
| Map Location | 6p21.33 |
| Variation Type | SNP |
| refSNP ID | HLA-B*07+/- |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | RR-MS,P-MS |
| Population | N/A |
| Sample Size | 60 MS patients/69 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 29587799 |
| Year | 2018 |
| Title | HLA alleles modulate EBV viral load in multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result |
The relationship between HLA alleles and viral parameters was exclusively seen in MS patient.A significantly higher EBV viral load could be detected in MS subjects carrying the HLA-B*07 allele (HLA-B*07+)compared to those not carrying this allele (HLA-B*07 |
| Mechanism/Pathway | N/A |
