Basic information of VDR :
| Official Symbol of Gene | VDR |
| Species | Homo sapiens |
| Entrez Gene ID | 7421 |
| Official Full Name | vitamin D receptor |
| Also known as | NR1I1; PPP1R163 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000111424 MIM:601769; AllianceGenome:HGNC:12679 |
| Map Location | 12q13.11 |
| Variation Type | polymorphisms |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | microsatellite markers |
| Disease | MS |
| Disease subtype | N/A |
| Population | Canadian |
| Sample Size | 236 sibling pairs from 187 families |
Literature information of multiple sclerosis :
| Pubmed ID | 10680811 |
| Year | 2000 |
| Title | Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | At the VDR locus, TDT analysis of the ApaI and TaqI polymorphisms did not show preferential transmission of any allele to affected offspring . |
| Mechanism/Pathway | A high prevalence of vitamin D deficiency has been demonstrated in MS patients.VDR is involved in the metabolism and function of vitamin D. |
