Details

Home Details


Basic information of IL2RA :

Official Symbol of Gene IL2RA
Species Homo sapiens
Entrez Gene ID 3559
Official Full Name interleukin 2 receptor subunit alpha
Also known as p55; CD25; IL2R; IMD41; TCGFR; IDDM10
Gene Type protein coding
dbXrefs Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008
Map Location 10p15.1
Variation Type SNP
refSNP ID rs2104286, rs35285258

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method iPlex SNP assay design system
Disease MS
Disease subtype RRMS,PPMS
Population Austria
Sample Size 883 patients/972 control individuals

Literature information of multiple sclerosis :

Pubmed ID 22411505
Year 2012
Title Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result We observed a trend for association of rs7090530 (IL2RA) with a younger age at MS onset.The additional non-MHC loci showing association without adjusting for multiple testing.
Mechanism/Pathway N/A