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Basic information of TRBV20OR9-2 :

Official Symbol of Gene TRBV20OR9-2
Species Homo sapiens
Entrez Gene ID 6962
Official Full Name T cell receptor beta variable 20/OR9-2 (non-functional)
Also known as TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O
Gene Type pseudo
dbXrefs Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197
Map Location 9p13.3
Variation Type allele
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample venous blood
Sample Detail N/A
Detected Method PCR,Southern blot hybridizations
Disease MS
Disease subtype N/A
Population Caucasian
Sample Size HLA-DR2+ MS patients(n = 51)/HLA-DR2- MS patients(n = 32)

Literature information of multiple sclerosis :

Pubmed ID 8101191
Year 1993
Title Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR V beta chain locus and HLA class II genes

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result The Vβ8/BamHI-Vβ11/BamHI subhaplotype frequencies differed significantly only in the HLA-DR2 + MS patients but not in the HLA-DR2- MS patients.
Mechanism/Pathway N/A