Basic information of LILRA3 :
| Official Symbol of Gene | LILRA3 |
| Species | Homo sapiens |
| Entrez Gene ID | 11026 |
| Official Full Name | leukocyte immunoglobulin like receptor A3 |
| Also known as | HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4 |
| Gene Type | protein coding |
| dbXrefs | MIM:604818 |
| Map Location | 19q13.4 |
| Variation Type | Deletion |
| refSNP ID | 6.7-kbp |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS, SPMS |
| Population | N/A |
| Sample Size | 309 patients / 379 healthy volunteers |
Literature information of multiple sclerosis :
| Pubmed ID | 23238213 |
| Year | 2012 |
| Title | 6.7-kbp deletion in LILRA3 (ILT6) gene is associated with later onset of the multiple sclerosis in a Polish population |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There were no significant differences between MS patients and controls. |
| Mechanism/Pathway | LILRA3 molecule (Leukocyte immunoglobulin–like subfamily A, member 3), belongs to the family of 13 highly homologous receptors–(LILRs).LILR molecules are broadly expressed on myeloid and lymphoid cells and play an important role in modulating innate and adoptive immune responses. |
