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Basic information of CD58 :

Official Symbol of Gene CD58
Species Homo sapiens
Entrez Gene ID 965
Official Full Name CD58 molecule
Also known as ag3; LFA3; LFA-3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000116815 MIM:153420; AllianceGenome:HGNC:1688
Map Location 1p13.1
Variation Type SNP
refSNP ID rs1414273

Sample information of multiple sclerosis:

Detected Sample blood and saliva samples
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype RRMS, SPMS
Population Kuwaiti
Sample Size 170 MS patients / 311 healthy controls

Literature information of multiple sclerosis :

Pubmed ID 32355262
Year 2020
Title Replication analysis of variants associated with multiple sclerosis risk

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result CD58 rs1414273A allele did not show any MS risk association in the replication Kuwaiti only population sample.CD58 rs1414273 genotypes were not significantly different with or without adjusting for sex.
Mechanism/Pathway N/A