Details

Home Details


Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type SNP
refSNP ID rs9271366

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method SNPline method
Disease MS
Disease subtype N/A
Population Australian
Sample Size 445 MS patients / 244 controls

Literature information of multiple sclerosis :

Pubmed ID 26199349
Year 2016
Title Population attributable fractions and joint effects of key risk factors for multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Positive
Result We identified a significant interaction between HLA-DR15 in predicting an FCD of CNS demyelination.
Mechanism/Pathway N/A