Basic information of MC1R :
| Official Symbol of Gene | MC1R |
| Species | Homo sapiens |
| Entrez Gene ID | 4157 |
| Official Full Name | melanocortin 1 receptor |
| Also known as | CMM5; MSH-R; SHEP2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000258839 MIM:155555; AllianceGenome:HGNC:6929 |
| Map Location | 16q24.3 |
| Variation Type | the red hair color (RHC) variant |
| refSNP ID | Arg151Cys, Arg160Trp, Asp294His |
Sample information of multiple sclerosis:
| Detected Sample | whole blood |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | MS |
| Disease subtype | N/A |
| Population | Australian |
| Sample Size | 136 cases with MS / 272 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 18711112 |
| Year | 2008 |
| Title | Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | Individually, only the Arg160Trp variant was associated with increased MS risk.The association between RHC variant genotype and MS was more evident for women than for men. |
| Mechanism/Pathway | N/A |
