Basic information of IL7R :

Official Symbol of Gene	IL7R
Species	Homo sapiens
Entrez Gene ID	3575
Official Full Name	interleukin 7 receptor
Also known as	ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024
Map Location	5p13.2
Variation Type	SNP
refSNP ID	504 C (GCA haplotype)

Sample information of multiple sclerosis:

Detected Sample	whole blood
Sample Detail	N/A
Detected Method	Real Time PCR
Disease	MS
Disease subtype	SPMS, PPMS
Population	northern European origin
Sample Size	12 patients with chronic progressive disease / 20 female healthy controls and 5 male healthy controls

Literature information of multiple sclerosis :

Pubmed ID	16075257
Year	2005
Title	Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	In the case control study, there was over-representation of the 504 T allele in PPMS and a non-significant trend towards over-representation of the C allele in SPMS.In healthy controls, no difference in promoter haplotype expression was detected, but in CPMS patients, a small but significant difference was detected in haplotype expression, with promoter haplotype GCA being the high expressor.
Mechanism/Pathway	N/A