Basic information of TLR3 :
| Official Symbol of Gene | TLR3 |
| Species | Homo sapiens |
| Entrez Gene ID | 7098 |
| Official Full Name | toll like receptor 3 |
| Also known as | CD283; IIAE2; IMD83 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000164342 MIM:603029; AllianceGenome:HGNC:11849 |
| Map Location | 4q35.1 |
| Variation Type | polymorphism |
| refSNP ID | 1377 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Han people of south China |
| Sample Size | 123 MS / 126 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 20197609 |
| Year | 2010 |
| Title | [TLR3c.1377, TLR9-1486, and TLR9 2848 gene polymorphisms and multiple sclerosis] |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | There was significant difference in genotype and allele distribution of TLR3c.1377 polymorphism between the MS patients and the controls, and the MS patients with T allele had a lower risk. |
| Mechanism/Pathway | N/A |
