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Basic information of IL17F :

Official Symbol of Gene IL17F
Species Homo sapiens
Entrez Gene ID 112744
Official Full Name interleukin 17F
Also known as ML1; ML-1; IL17A; CANDF6; IL-17F
Gene Type protein coding
dbXrefs Ensembl:ENSG00000112116 MIM:606496; AllianceGenome:HGNC:16404
Map Location 6p12.2
Variation Type SNP
refSNP ID rs763780

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Southern Han Chinese
Sample Size 69 MS patients / 131 controls

Literature information of multiple sclerosis :

Pubmed ID 22118860
Year 2011
Title Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese--a case control study

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result The difference between C-MS and controls did not quite reach statistical significance.
Mechanism/Pathway Multiple sclerosis (MS) is autoimmune demyelinating diseases of the central nervous system with complex pathogenesis.IL-17F has been shown to play an important role in the pathogenesis of certain autoimmune diseases.