Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 3559 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | interleukin 2 receptor subunit alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs12722489 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | Real-time PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Japanese |
| Sample Size | 115 MS patients / 238 healthy controls. |
Literature information of multiple sclerosis :
| Pubmed ID | 24332945 |
| Year | 2014 |
| Title | Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | The MS patients with the rs12722489-CC genotype showed a significantly higher annualized relapse rate than the MS patients with the non-CC genotype.The increased relapse rates in the rs12722489-CC genotype MS patients were only observed in females, and not in males. |
| Mechanism/Pathway | N/A |
