Basic information of IL7R :
| Official Symbol of Gene | IL7R |
| Species | Homo sapiens |
| Entrez Gene ID | 3575 |
| Official Full Name | interleukin 7 receptor |
| Also known as | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024 |
| Map Location | 5p13.2 |
| Variation Type | SNP |
| refSNP ID | rs6897932 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood leucocytes |
| Sample Detail | N/A |
| Detected Method | high multiplexed iPlexes |
| Disease | MS |
| Disease subtype | N/A |
| Population | German and French |
| Sample Size | 206 MS patients / 540 MS trios / 605 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 18354419 |
| Year | 2008 |
| Title | IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The SNP rs6897932 located within the IL7RA gene exhibits a significant association in the French trios and a positive trend in the German sample. |
| Mechanism/Pathway | Variations in the interleukin-7 receptor-a chain (IL7RA) were demonstrated to confer a risk for MS in candidate gene approaches and a whole genome screen. |
