Basic information of IL4 :
| Official Symbol of Gene | IL4 |
| Species | Homo sapiens |
| Entrez Gene ID | 3565 |
| Official Full Name | interleukin 4 |
| Also known as | BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000113520 MIM:147780; AllianceGenome:HGNC:6014 |
| Map Location | 5q31.1 |
| Variation Type | allele |
| refSNP ID | IL-4 (-590) |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood leukocytes |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMS, PPMS, SPMS |
| Population | Iranian |
| Sample Size | 270 MS patients / 542 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 17295710 |
| Year | 2007 |
| Title | TNF-alpha, TNF-beta and IL-4 gene polymorphisms in Iranian patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | Allelic and genotypic frequencies for this polymorphism was similar in patients with MS and population controls or among different types of the disease. The mentioned functional polymorphism is not likely to cause susceptibility to MS in the Iranian population. |
| Mechanism/Pathway | The anti-inflammatory cytokines, such as interleukin-4 (IL-4), has a beneficial role in preventing lesion formation or relapse of the disease. |
