Basic information of CD86 :

Official Symbol of Gene	CD86
Species	Homo sapiens
Entrez Gene ID	942
Official Full Name	CD86 molecule
Also known as	B70; B7-2; B7.2; LAB72; CD28LG2
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000114013 MIM:601020; AllianceGenome:HGNC:1705
Map Location	3q13.33
Variation Type	SNP
refSNP ID	rs928264

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	N/A
Detected Method	Infinium 660K BeadChip or HumanOmniExpress BeadChip
Disease	POMS
Disease subtype	N/A
Population	N/A
Sample Size	334 POMS cases and 565 controls

Literature information of multiple sclerosis :

Pubmed ID	35000467
Year	2022
Title	Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Negative
Result	Without high ozone exposure, the presence of the GG genotype of CD86 SNP did not significantly increase the odds of having POMS.Conversely, without the GG genotype of CD86 SNP, high ozone exposure was not associated with increased odds of POMS.When both GG genotype of CD86 SNP and high ozone exposure were present, the odds ratio of POMS increased to 4.06.
Mechanism/Pathway	N/A