Basic information of GAS5 :
| Official Symbol of Gene | GAS5 |
| Species | Homo sapiens |
| Entrez Gene ID | 60674 |
| Official Full Name | GAS5 |
| Also known as | SNHG2; NCRNA00030 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000234741 MIM:608280; AllianceGenome:HGNC:16355 |
| Map Location | 1q25.1 |
| Variation Type | SNP |
| refSNP ID | rs2067079 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | T-ARMS-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Iranian |
| Sample Size | 410 MS patients/400 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30790644 |
| Year | 2019 |
| Title | GAS5 genomic variants and risk of multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | There was a significant over-representation of the rs2067079 T allele in MS patients compared with healthy individuals .This SNP was associated with MS risk in co-dominant and recessive models. |
| Mechanism/Pathway | The T allele of the rs2067079 would change the secondary structure of the transcript and upsurge the minimum free energy. Notably this SNP alters the binding site for a number of microRNAs. |
