Basic information of CBLB :
| Official Symbol of Gene | CBLB |
| Species | Homo sapiens |
| Entrez Gene ID | 868 |
| Official Full Name | Cbl proto-oncogene B |
| Also known as | Cbl-b; RNF56; Nbla00127 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000114423 MIM:604491; AllianceGenome:HGNC:1542 |
| Map Location | 3q13.11 |
| Variation Type | SNP |
| refSNP ID | rs12487066 |
Sample information of multiple sclerosis:
| Detected Sample | saliva |
| Sample Detail | N/A |
| Detected Method | real-time PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 137 RRMS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 34169444 |
| Year | 2021 |
| Title | Pharmacogenetic Predictors of Response to Interferon Beta Therapy in Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | The CBLB-rs12487066 gene polymorphisms showed a trend to association with change in the EDSS after 24 months of IFN treatment, but non-signifcant. |
| Mechanism/Pathway | N/A |
