Basic information of OAS1 :
| Official Symbol of Gene | OAS1 |
| Species | Homo sapiens |
| Entrez Gene ID | 4938 |
| Official Full Name | 2'-5'-oligoadenylate synthetase 1 |
| Also known as | OIAS; IFI-4; OIASI; IMD100; E18/E16 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000089127 MIM:164350; AllianceGenome:HGNC:8086 |
| Map Location | 12q24.13 |
| Variation Type | SNP |
| refSNP ID | rs10774671 |
Sample information of multiple sclerosis:
| Detected Sample | saliva |
| Sample Detail | N/A |
| Detected Method | real-time PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 137 RRMS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 34169444 |
| Year | 2021 |
| Title | Pharmacogenetic Predictors of Response to Interferon Beta Therapy in Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | The OAS1-rs10774671 gene polymorphism did not predict the variation of the individual response to IFN-β or change in the EDSS. |
| Mechanism/Pathway | N/A |
