Basic information of TNFRSF10A :
| Official Symbol of Gene | TNFRSF10A |
| Species | Homo sapiens |
| Entrez Gene ID | 8797 |
| Official Full Name | TNF receptor superfamily member 10a |
| Also known as | DR4; APO2; CD261; TRAILR1; TRAILR-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000104689 MIM:603611; AllianceGenome:HGNC:11904 |
| Map Location | 8p21.3 |
| Variation Type | SNP |
| refSNP ID | rs20576 |
Sample information of multiple sclerosis:
| Detected Sample | saliva |
| Sample Detail | N/A |
| Detected Method | real-time PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 137 RRMS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 34169444 |
| Year | 2021 |
| Title | Pharmacogenetic Predictors of Response to Interferon Beta Therapy in Multiple Sclerosis |
Results of multiple sclerosis :
| Risk Type | Treatment risk |
| Main Result | Negative |
| Result | The TNFRSF10Ars20576 gene polymorphisms showed a trend to association with change in the EDSS after 24 months of IFN treatment,but non-signifcant. |
| Mechanism/Pathway | N/A |
