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Basic information of HLA-DRB1 :

Official Symbol of Gene HLA-DRB1
Species Homo sapiens
Entrez Gene ID 3123
Official Full Name major histocompatibility complex, class II, DR beta 1
Also known as SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location 6p21.32
Variation Type allele
refSNP ID DRB1*1501

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype RRMS,RPMS
Population Japanese
Sample Size 121 patients /125 healthy controls.

Literature information of multiple sclerosis :

Pubmed ID 18952831
Year 2008
Title Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result The frequency of the DRB1*1501 allele was insignificantly increased in the Barkhof brain lesion–positive group.
Mechanism/Pathway N/A