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Basic information of IL1B :

Official Symbol of Gene IL1B
Species Homo sapiens
Entrez Gene ID 3553
Official Full Name interleukin 1 beta
Also known as IL-1; IL1F2; IL1beta; IL1-BETA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992
Map Location 2q14.1
Variation Type polymorphism
refSNP ID -511 C/T

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 399 patients /439 HCs

Literature information of multiple sclerosis :

Pubmed ID 11183041
Year 2000
Title Lack of association between IL-1A and IL-1B promoter polymorphisms and multiple sclerosis

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result As for the IL-1B polymorphism, the gene frequency of the 73 benign patients was also similar to those of the 82 non benign patients with multiple sclerosis. IL-1B genotypes seemed to aVect the distribution of the age at multiple sclerosis onset.
Mechanism/Pathway N/A