Details

Home Details


Basic information of SYN3 :

Official Symbol of Gene SYN3
Species Homo sapiens
Entrez Gene ID 8224
Official Full Name synapsin III
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000185666 MIM:602705; AllianceGenome:HGNC:11496
Map Location 22q12.3
Variation Type SNP
refSNP ID rs133946

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population Spanish
Sample Size 221 Spanish MS patients/373 controls

Literature information of multiple sclerosis :

Pubmed ID 18755822
Year 2008
Title Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients

Results of multiple sclerosis :

Risk Type Disease risk
Main Result Negative
Result The rs133946C/C haplotype was overrepresented in the control group as compared with the MS group, but this difference did not reach statistical significance.
Mechanism/Pathway Synapsins are a family of four neuron-specific phosphoproteins that play a role in short-term regulation of neurotransmitter release.