Basic information of APOC2 :
| Official Symbol of Gene | APOC2 |
| Species | Homo sapiens |
| Entrez Gene ID | 344 |
| Official Full Name | apolipoprotein C2 |
| Also known as | APO-CII; APOC-II |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000234906 MIM:608083; AllianceGenome:HGNC:609 |
| Map Location | 19q13.32 |
| Variation Type | allele |
| refSNP ID | (TG)n(AG)m allele |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | French |
| Sample Size | 74 MS patients / 102 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 10335523 |
| Year | 1999 |
| Title | Chromosome 19 locus apolipoprotein C-II association with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The distribution of microsatellite alleles differed between patients and controls , showing a signicant effect with MS due to the increased frequency of the allele 6 and a decrease frequency of allele 1. |
| Mechanism/Pathway | APOE has a special relevance to the nervous system: evidence suggests APOE-dependent uptake of lipoproteins may play an important role in the development and maintenace of the nervous system, and in responses to both peripheral and central nervous injury. |
