Basic information of TNFSF10 :
| Official Symbol of Gene | TNFSF10 |
| Species | Homo sapiens |
| Entrez Gene ID | 8743 |
| Official Full Name | TNF superfamily member 10 |
| Also known as | TL2; APO2L; CD253; TANCR; TRAIL; Apo-2L; TNLG6A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000121858 MIM:603598; AllianceGenome:HGNC:11925 |
| Map Location | 3q26.31 |
| Variation Type | SNP |
| refSNP ID | 1595C/T |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-RFLP |
| Disease | MS |
| Disease subtype | RRMS,SPMS |
| Population | Japanese |
| Sample Size | 128 patients / 158 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 16040132 |
| Year | 2005 |
| Title | TNF-related apoptosis inducing ligand (TRAIL) gene polymorphism in Japanese patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The presence of the CC genotype at position 1595 in exon 5 represents a higher risk of MS. |
| Mechanism/Pathway | N/A |
