Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | allele |
| refSNP ID | HLA-DRB1*15 +/- |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | SSP-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spain |
| Sample Size | 326 MS patients / 226 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 27569565 |
| Year | 2016 |
| Title | Month of birth, HLA-DRB1*15 locus and risk of multiple sclerosis in offspring |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | MS patients carrying HLA-DRB1*15 allele were more frequently born in December.Controls carrying HLA-DRB1*15 allele were less frequently born in December than non-carrier controls.Thus, December was confirmed as the common month of birth for HLA-DRB1*15-non-carrier controls and MS HLA-DRB1*15-carrier patients. |
| Mechanism/Pathway | N/A |
