Basic information of HLA-DQA1 :
| Official Symbol of Gene | HLA-DQA1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3117 |
| Official Full Name | major histocompatibility complex, class II, DQ alpha 1 |
| Also known as | DQA1; DQ-A1; CELIAC1; HLA-DQA; HLA-DQB1; HLA-DQA1* |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196735 MIM:146880; AllianceGenome:HGNC:4942 |
| Map Location | 6p21.32 |
| Variation Type | allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RFLP,PCR-SSP |
| Disease | MS |
| Disease subtype | CPMS |
| Population | Iranian |
| Sample Size | 43 patients/100 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 9777330 |
| Year | 1998 |
| Title | HLA class II (DRB1, DQA1 and DQB1) associated genetic susceptibility in Iranian multiple sclerosis (MS) patients |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | The frequency of the DQA1*0102 haplotype had increased significantly among the DR2-positive MS patients compared with the DR2-positive control group.The DQA1*0103 haplotype was negatively associated with MS. |
| Mechanism/Pathway | N/A |
