Basic information of IL2RA :
| Official Symbol of Gene | IL2RA |
| Species | Homo sapiens |
| Entrez Gene ID | 3559 |
| Official Full Name | interleukin 2 receptor subunit alpha |
| Also known as | interleukin 2 receptor subunit alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000134460 MIM:147730; AllianceGenome:HGNC:6008 |
| Map Location | 10p15.1 |
| Variation Type | SNP |
| refSNP ID | rs2104286 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Southern Han Chinese |
| Sample Size | 78 MS cases / 133 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24257225 |
| Year | 2013 |
| Title | IL2RA Allele Increases Risk of Neuromyelitis Optica in Southern Han Chinese |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There were no significant differences. |
| Mechanism/Pathway | IL2RA genes are involved in T cell regulation which plays an important role in the pathogenesis of autoimmune diseases besides MS.Han Chinese MS and patients have a different genetic background to Caucasian and even other Asian patients in other countries. |
