Basic information of IL7R :
| Official Symbol of Gene | IL7R |
| Species | Homo sapiens |
| Entrez Gene ID | 3575 |
| Official Full Name | interleukin 7 receptor |
| Also known as | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000168685 MIM:146661; AllianceGenome:HGNC:6024 |
| Map Location | 5p13.2 |
| Variation Type | SNP |
| refSNP ID | rs6897932 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Southern Han Chinese |
| Sample Size | 78 MS cases / 133 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24257225 |
| Year | 2013 |
| Title | IL2RA Allele Increases Risk of Neuromyelitis Optica in Southern Han Chinese |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There were no significant differences. |
| Mechanism/Pathway | IL7RA genes are involved in T cell regulation which plays an important role in the pathogenesis of autoimmune diseases besides MS.Han Chinese MS and patients have a different genetic background to Caucasian and even other Asian patients in other countries. |
