Basic information of IL6 :
| Official Symbol of Gene | IL6 |
| Species | Homo sapiens |
| Entrez Gene ID | 3569 |
| Official Full Name | interleukin 6 |
| Also known as | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018 |
| Map Location | 7p15.3 |
| Variation Type | polymorphism |
| refSNP ID | C allele present or absent |
Sample information of multiple sclerosis:
| Detected Sample | leukocyte |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | RRMS,PPMS,SPMS |
| Population | German caucasian |
| Sample Size | 96 MS patients / 106 ethnically matched healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 11072134 |
| Year | 2000 |
| Title | No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3'flanking region of the interleukin-6 gene in patients with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | There were no differences in the allelic distribution of the IL-6 gene C allele between MS patients and healthy controls. |
| Mechanism/Pathway | A dysregulation of IL-6 might contribute to MS pathogenesis. |
