Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	allele
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	peripheral blood mononuclear cells (PBMC)
Sample Detail	N/A
Detected Method	SSP-PCR
Disease	MS
Disease subtype	N/A
Population	Caucasian-Italians
Sample Size	512 MS patients / 249 HC

Literature information of multiple sclerosis :

Pubmed ID	21664963
Year	2011
Title	Vitamin D receptor (VDR) gene SNPs influence VDR expression and modulate protection from multiple sclerosis in HLA-DRB1*15-positive individuals

Results of multiple sclerosis :

Risk Type	Disease risk
Main Result	Positive
Result	Results showed the presence of a significantly higher frequency of -DRB1-11 alleles in HC compared to MS patients. Conversely DRB1-15 was more frequent in MS patients then in HC.The distribution of the frequencies of the other HLA-DRB1 alleles was not different between patients and controls.
Mechanism/Pathway	N/A