Basic information of HLA-DRB1 :
| Official Symbol of Gene | HLA-DRB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 3123 |
| Official Full Name | major histocompatibility complex, class II, DR beta 1 |
| Also known as | SS1; DRB1; HLA-DRB; HLA-DR1B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948 |
| Map Location | 6p21.32 |
| Variation Type | allele |
| refSNP ID | DRB1*1501 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR-SSO and PCR-SSP |
| Disease | MS |
| Disease subtype | N/A |
| Population | Spanish |
| Sample Size | 43 MS / 107 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 14752708 |
| Year | 2004 |
| Title | [The relation between the HLA-DRB1*1501 allele and the severity of multiple sclerosis in a sample of the Spanish population from the Balearic Islands: the influence exerted by sex] |
Results of multiple sclerosis :
| Risk Type | Phenotypic risk |
| Main Result | Positive |
| Result | DRB1*1501 is associated with the presence of MS only in females and with lower severity of the disease only in males. |
| Mechanism/Pathway | N/A |
