Basic information of TRBV20OR9-2 :
| Official Symbol of Gene | TRBV20OR9-2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6962 |
| Official Full Name | T cell receptor beta variable 20/OR9-2 (non-functional) |
| Also known as | TCR; TRB; CDR3; TCRB; TCRBV2O; TCRBV20S2; TCRBV2S2O |
| Gene Type | pseudo |
| dbXrefs | Ensembl:ENSG00000205274 IMGT/GENE-DB:TRBV20/OR9-2; AllianceGenome:HGNC:12197 |
| Map Location | 9p13.3 |
| Variation Type | polymorphism |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | RFLPs |
| Disease | MS |
| Disease subtype | N/A |
| Population | Caucasian |
| Sample Size | 565 patients / 179 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 15175643 |
| Year | 2004 |
| Title | TCR beta polymorphisms and multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Negative |
| Result | A total of 267 families with two or more siblings with multiple sclerosis (MS) were genotyped with 14 restriction fragment length polymorphisms at the TCR beta locus.A nonparametric linkage analysis of the data showed no evidence for linkage to this locus . No significant allelic or haplotype transmissions were observed in the total sample of 565 patients. |
| Mechanism/Pathway | An initial positive association of a TCR a rearrangement in multiple sclerosis brains (MS). |
