Basic information of EBNA-2 :
| Official Symbol of Gene | EBNA-2 |
| Species | Human gammaherpesvirus 4 |
| Entrez Gene ID | 3783761 |
| Official Full Name | nuclear antigen EBNA-2 |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | N/A |
| Map Location | HHV4_EBNA-2 |
| Variation Type | allele |
| refSNP ID | N/A |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood mononuclear cells (PBMC) |
| Sample Detail | N/A |
| Detected Method | seminested PCR approach and Sanger sequencing |
| Disease | MS |
| Disease subtype | RRMS,PPMS |
| Population | Italians |
| Sample Size | 53 patients / 38 HDs |
Literature information of multiple sclerosis :
| Pubmed ID | 25740864 |
| Year | 2015 |
| Title | Epstein-Barr virus genetic variants are associated with multiple sclerosis |
Results of multiple sclerosis :
| Risk Type | Disease risk |
| Main Result | Positive |
| Result | MS risk significantly correlated with an excess of 1.2 allele and underrepresentation of 1.3B allele. |
| Mechanism/Pathway | EBNA2 sequence mutations are known to affect interaction with host proteins. |
