Details

Home Details


Basic information of HLA-A :

Official Symbol of Gene HLA-A
Species Homo sapiens
Entrez Gene ID 3105
Official Full Name major histocompatibility complex, class I, A
Also known as HLAA
Gene Type protein coding
dbXrefs Ensembl:ENSG00000206503 MIM:142800; AllianceGenome:HGNC:4931
Map Location 6p22.1
Variation Type allele
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample peripheral granulocytes
Sample Detail N/A
Detected Method PCR-SSOP
Disease MS
Disease subtype RRMS,RPMS
Population Japanese
Sample Size 89 Western type MS patients / 57 Asian type MS patients / 146 healthy

Literature information of multiple sclerosis :

Pubmed ID 9894852
Year 1998
Title Molecular analysis of HLA class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type)

Results of multiple sclerosis :

Risk Type Disease risk ; Phenotypic risk
Main Result Negative
Result No statistically significant difference in the frequencies of HLA-A alleles was found between controls and total MS patients, Western type MS patients, Asian type MS patients or between the two subtypes.
Mechanism/Pathway N/A