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Basic information of HLA-B :

Official Symbol of Gene HLA-B
Species Homo sapiens
Entrez Gene ID 3106
Official Full Name major histocompatibility complex, class I, B
Also known as AS; HLAB; B-4901
Gene Type protein coding
dbXrefs Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932
Map Location 6p21.33
Variation Type allele
refSNP ID N/A

Sample information of multiple sclerosis:

Detected Sample peripheral granulocytes
Sample Detail N/A
Detected Method PCR-SSOP
Disease MS
Disease subtype RRMS,RPMS
Population Japanese
Sample Size 89 Western type MS patients / 57 Asian type MS patients / 146 healthy

Literature information of multiple sclerosis :

Pubmed ID 9894852
Year 1998
Title Molecular analysis of HLA class I (HLA-A and -B) and HLA class II (HLA-DRB1) genes in Japanese patients with multiple sclerosis (Western type and Asian type)

Results of multiple sclerosis :

Risk Type Disease risk ; Phenotypic risk
Main Result Negative
Result After Bonferroni corrections were made there was no statistical significance in the association between HLA-B*5101 alleles and MS in total MS patients and controls.In addition there was no statistical significant difference in frequencies of HLA-B alleles between the two subgroups.
Mechanism/Pathway N/A