Basic information of HLA-DRB1 :

Official Symbol of Gene	HLA-DRB1
Species	Homo sapiens
Entrez Gene ID	3123
Official Full Name	major histocompatibility complex, class II, DR beta 1
Also known as	SS1; DRB1; HLA-DRB; HLA-DR1B
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196126 MIM:142857; AllianceGenome:HGNC:4948
Map Location	6p21.32
Variation Type	DNA methylation at CpG dinucleotides
refSNP ID	N/A

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	N/A
Detected Method	pyrosequencing,RT-PCR
Disease	MS
Disease subtype	N/A
Population	Canadian
Sample Size	48 benign MS patients / 20 malignant MS patients

Literature information of multiple sclerosis :

Pubmed ID	20394989
Year	2010
Title	No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5

Results of multiple sclerosis :

Risk Type	Phenotypic risk
Main Result	Negative
Result	We found no significant effect of DNA methylation across HLA-DRB1*1501 on severity.
Mechanism/Pathway	N/A